diacylglycerol acyltransferase (DGAT-1) inhibitor
CAS:892489-52-0
分子式:C23H22F2N4O4
分子量:456.44
纯度:98%
存储:Store at -20°C
Background:
AZD3988 is a diacylglycerol acyl transferase-1 (DGAT-1) inhibitor with IC50s of 6, 5, 11 nM for human, rat, mouse, respectively[1].
参考文献:
[1]. McCoull W, et al. Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3873-8.