Selective MEK inhibitor
CAS:934660-94-3
分子式:C21H21F3IN3O2
分子量:531.31
纯度:98%
存储:Store at -20°C
Background:
Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor.
参考文献:
[1]. Hoeflich KP, et al. Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition. Cancer Res. 2012 Jan 1;72(1):210-9.