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Pyridostatin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pyridostatin图片
CAS NO:1085412-37-8
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品名称
RR-82, RR82, RR 82
产品介绍

生物活性

Pyridostatin是一种G-quadruplexe稳定剂,无细胞试验中Kd为490 nM,其以一系列原癌基因,包括c-kit,K-ras 和 Bcl-2为靶点。可通过诱导复制和转录依赖性DNA损伤来促进人类癌细胞的生长停滞。

化学数据

目录号A12717
M. Wt596.64
FormulaC31H32N8O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1085412-37-8
SynonymsRR-82, RR82, RR 82
SMILESNCCOC1=CC(NC(C2=NC(C(NC3=CC(OCCN)=C(C=CC=C4)C4=N3)=O)=CC(OCCN)=C2)=O)=NC5=C1C=CC=C5

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM16.76 mL83.8 mL167.61 mL
0.5 mM3.35 mL16.76 mL33.52 mL
1 mM1.68 mL8.38 mL16.76 mL
5 mM0.34 mL1.68 mL3.35 mL

*The above data is based on the productmolecular weight 596.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.