C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6.
CAS：34227-72-0
分子式：C32H63NO3
分子量：509.9
纯度：98%
存储：Store at -20°C

Background:

C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6. During nutrient-deprivation-induced necroptosis in MEF cells, C14 ceramide levels increase in a time-dependent manner. C14 ceramide plasma levels were reduced in obese patients with or without diabetes following a 12-week supervised exercise training program, correlating positively with weight and fat loss and negatively with an increase in insulin sensitivity. In contrast, plasma levels were higher in Parkinson’s disease patients with dementia than those without dementia and higher levels were correlated with deficits in memory.