Bevenopran, formerly known as CB-5945, ADL-5945, MK-2402, OpRA III, is a peripherally selective μ- and δ-opioid receptor antagonist that was under development by Cubist Pharmaceuticals for the treatment of chronic opioid-induced constipation. It reached phase III clinical trials for this indication before being discontinued. References: Siemens W, Gaertner J, Becker G. Advances in pharmacotherapy for opioid-induced constipation - a systematic review. Expert Opin Pharmacother. 2015 Mar;16(4):515-32. doi: 10.1517/14656566.2015.995625. Epub 2014 Dec 24. Review. PubMed PMID: 25539282.

纯度：≥98%

CAS：676500-67-7