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Cucurbitacin IIb
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cucurbitacin IIb图片
CAS NO:50298-90-3
包装:20mg
规格:98%
市场价:4005元
分子量:520.71

产品介绍
Extracted?from?Hemsleya amabilis Diels root tuber;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:50298-90-3
分子式:C30H48O7
分子量:520.71
纯度:98%
存储:Store at -20°C

Background:

Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α[1].


参考文献:
[1]. Wang Y, et al. Cucurbitacin IIb exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes. PLoS One. 2014 Feb 25;9(2):e89751.