inositol hexakisphosphate kinase (IP6K) inhibitor
CAS:519178-28-0
分子式:C20H16F3N7O2
分子量:443.38
纯度:98%
存储:Store at -20°C
Background:
TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 μM and 10.2 μM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes[1].
参考文献:
[1]. Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901.