7-Methylguanine是DNA甲基化的代谢产物。它可以通过甲基化试剂产生,并用作蛋白质-DNA相互作用的探针和DNA测序方法的关键组分。
CAS:578-76-7
分子式:C6H7N5O
分子量:165.15
纯度:98%
存储:Store at -20°C
Background:
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein-DNA interactions and a key component of DNA sequencing method.
[1]. Lee S, et al. Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J Am Chem Soc. 2008 Sep 3;130(35):11570-1.