CAS NO: | 2095244-42-9 |
规格: | 98% |
分子量: | 598.75 |
包装 | 价格(元) |
1g | 电议 |
100mg | 电议 |
2g | 电议 |
500mg | 电议 |
Background:
E3 ligase Ligand 12 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 12 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.