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Chlortetracycline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Chlortetracycline图片
CAS NO:57-62-5
规格:98%
分子量:478.9
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
Chlortetracycline is a broad-spectrum antibiotic originally isolated from S.
CAS:57-62-5
分子式:C22H23ClN2O8
分子量:478.9
纯度:98%
存储:Store at -20°C

Background:

Chlortetracycline is a broad-spectrum antibiotic originally isolated from S. aureofaciens. It inhibits growth of both Gram-positive and Gram-negative bacteria at a range of 0.1-100 μg/ml against A. aerogenes, D. pneumoniae, E. coli, K. pneumoniae, P. morganii, and several species of Haemophilus, Neisseria, Salmonella, and Staphylococcus. Chlortetracycline protects mice from infection by various strains of S. aureus with protective doses (PD50s) of 0.2-7.5 mg/kg, and from infection by E. coli (PD50 = 3 mg/kg) and K. pneumoniae (PD50 = 75 mg/kg). It acts by inhibiting protein synthesis, and it binds to a single site on the 30S ribosome subunit. Chlortetracycline is an ionophore and is selective for calcium over sodium, potassium, magnesium, strontium, and barium. It transports calcium from an aqueous phase into an organic phase environment or into multilamellar vesicles. Chlortetracycline is also a fluorescent dye that can be used to monitor calcium flux.