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Peiminine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Peiminine图片
CAS NO:18059-10-4
包装:20mg
规格:98%
市场价:1786元
分子量:429.63

产品介绍
Extracted from Fritillaria;Store the product in sealed,cool and dry condition
CAS:18059-10-4
分子式:C27H43NO3
分子量:429.63
纯度:98%
存储:Store at -20°C

Background:

Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.


参考文献:
[1]. Guo H, et al. Peiminine ameliorates bleomycin-induced acute lung injury in rats. Mol Med Rep. 2013 Apr;7(4):1103-10.