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Nemadipine A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nemadipine A图片
CAS NO:54280-71-6
规格:98%
分子量:419.3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C.
CAS:54280-71-6
分子式:C19H18F5NO4
分子量:419.3
纯度:98%
存储:Store at -20°C

Background:

Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel α1-subunit in the C. elegans genome. It also inhibits L-type calcium channels in chick ciliary neurons. Nemadipine A increases TRAIL-induced cytotoxicity and synergistically enhances caspase-8 and caspase-3 activation in a concentration-dependent manner in H1299 lung adenocarcinoma cells. It also decreases Survivin expression when used alone or in combination with TRAIL in A549 cells.