CAS NO: | 1259296-46-2 |
规格: | 98% |
分子量: | 299.3 |
包装 | 价格(元) |
500ug | 电议 |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Background:
HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, as well as other substrates. In this way, it impacts development, proliferation, invasion, and tumorigenesis. HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC50 = 36 nM) that poorly blocks other HDAC enzymes. It is cell permeable, inhibiting the acetylation of tubulin in cells with an IC50 value of 210 nM.