B-I09 is a novel cell permeable IRE-1 RNase inhibitor, blocking IRE-1/XBP1 pathway. References: Tang CH, Ranatunga S, Kriss CL, Cubitt CL, Tao J, Pinilla-Ibarz JA, Del Valle JR, Hu CC. Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. J Clin Invest. 2014 Jun;124(6):2585-98. doi: 10.1172/JCI73448. Epub 2014 May 8. PubMed PMID: 24812669; PubMed Central PMCID: PMC4038575.
纯度:≥98%
CAS:1607803-67-7