Bacopaside II 是一种药用植物 Bacopa monnieri 的提取物，它阻断 Aquaporin-1 (AQP1) 水通道并阻碍表达 AQP1 的细胞迁移。Bacopaside II 还会诱导细胞周期停滞和细胞凋亡。
CAS：382146-66-9
分子式：C47H76O18
分子量：929.1
纯度：98%
存储：Store at -20°C

Background:

Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis[1][2].

[1]. Palethorpe HM, et al. The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis. Int J Mol Sci. 2018 Feb 26;19(3). pii: E653. [2]. Smith E, et al. The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis. Cells. 2018 Jul 21;7(7). pii: E81.