Mitochonic Acid 35 is a dual inhibitor of TNF-α and TGF-β1. It acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation. References: Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe T. A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β(1) pathways. Sci Rep. 2017 May 15;7(1):1884. doi: 10.1038/s41598-017-01702-7. PubMed PMID: 28507324; PubMed Central PMCID: PMC5432497.

纯度：≥98%

CAS：1611470-23-5