E3LigaseLigand-LinkerConjugate11是一种合成化合物,由E3泛素连接酶的配体和一个PROTAC接头组成,该化合物将靶蛋白和泛素化机制结合在一起。
CAS:1835705-61-7
分子式:C39H61ClN4O6S
分子量:749.44
纯度:98%
存储:Store at -20°C
Background:
E3 Ligase Ligand-Linker Conjugate 11 is a synthesized compound which incorporates a ligand for the E3 ubiquitin ligase and a PROTAC linker to bring together target protein and ubiquitinating machinery.
[1]. Ashton C. Lai, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11; 55(2): 807-810.