E3ligaseLigand-LinkerConjugates7FreeBase是一种合成化合物,包含E3泛素连接酶配体与PROTAC连接物,可以将靶蛋白与泛素化机制结合起来。详细信息请参考专利文献US20170008904A1中Example3中合成化合物A1895的具体步骤。
CAS:2010159-57-4
分子式:C32H49N5O8S
分子量:663.83
纯度:98%
存储:Store at -20°C
Background:
E3 ligase Ligand-Linker Conjugates 7 Free Base is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.
E3 ligase Ligand-Linker Conjugates 7 Free Base, extracted from patent US20170008904A1, can be used in the synthesis of compound A1895 in example 3[1].
[1]. Crew, Andrew P, et al. MDM2-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. US20170008904A1.