BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. BIBB 515 inhibits 2,3-oxidosqualene cyclase and has applications to cholesterol lowering. References: Eisele B, Budzinski R, Müller P, Maier R, Mark M. Effects of a novel 2,3-oxidosqualene cyclase inhibitor on cholesterol biosynthesis and lipid metabolism in vivo. J Lipid Res. 1997 Mar;38(3):564-75. PubMed PMID: 9101437.

纯度：≥98%

CAS：156635-05-1