JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
CAS:202592-23-2
分子式:C19H17ClN4O2S
分子量:400.88
纯度:98%
存储:Store at -20°C
Background:
JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
参考文献:
[1]. James Elliott Bradner, et al. Male contraceptive compositions and methods of use. Patent WO 2011143657 A1.