RegorafénibN-oxydeM2是Regorafenib的活性代谢物。Regorafenib是一种多靶点抑制剂，对于VEGFR1/2/3，PDGFRβ，Kit，RET和Raf-1的IC50值分别为13/4.2/46，22，7，1.5和2.5nM。
CAS：835621-11-9
分子式：C21H15ClF4N4O4
分子量：498.81
纯度：98%
存储：Store at -20°C

Background:

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

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