Bicyclomycin (Bicozamycin) is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium, Micrococcus luteusn that was extracted from Streptomyces sapporonesis and Streptomyces aizumenses in 1972. It belongs to a class of naturally occurring 2,5-diketopiperazines, that are among the most numerous of all the naturally occurring peptide antibiotics. This clinically useful antibiotic is rapidly absorbed in man when given intramuscularly, has low toxicity and has been used to treat diarrhea in humans and bacterial diarrhea in calves and pigs. References: Tran L, van Baarsel JA, Washburn RS, Gottesman ME, Miller JH. Single-gene deletion mutants of Escherichia coli with altered sensitivity to bicyclomycin, an inhibitor of transcription termination factor Rho. J Bacteriol. 2011 May;193(9):2229-35. doi: 10.1128/JB.01463-10. Epub 2011 Feb 25. PubMed PMID: 21357484; PubMed Central PMCID: PMC3133090.

纯度：≥98%

CAS：38129-37-2