Homo-PROTACcereblondegrader1(compound15a)是CRBN蛋白的高效降解剂，对IKZF1和IKZF3的影响很小。
CAS：2244520-98-5
分子式：C32H32N6O10
分子量：660.63
纯度：98%
存储：Store at -20°C

Background:

Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3[1].

[1]. Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.