3,4-Dihydroxybenzeneaceticacid是多巴胺主要的代谢物。
CAS：102-32-9
分子式：C8H8O4
分子量：168.15
纯度：98%
存储：Store at -20°C
Background:
3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine.
3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine. Cerebrospinal fluid (CSF) 3,4-Dihydroxybenzeneacetic acid (DOPAC) is derived from intra-neuronal metabolism of cytoplasmic dopamine, and acts as a sensitive and specific biomarker of central dopamine deficiency[1].
[1]. Goldstein DS, et al. Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies. Parkinsonism Relat Disord. 2016 Oct;31:79-86.
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