BEBT-908是一种选择性的PI3Kα抑制剂，IC50<0.1μM,也抑制HDAC(0.1μM≤IC50≤1μM)，详细信息请参考专利文献US/20120088764A1中的化合物243。
CAS：1235449-52-1
分子式：C23H25N9O3S
分子量：507.57
纯度：98%
存储：Store at -20°C

Background:

BEBT-908 is a selective PI3Kα inhibitor extracted from patent US/20120088764A1, Compound 243, has an IC50<0.1 μM, PI3Kα inhibitor 1 also inhibits HDAC (0.1 μM≤IC50≤1 μM) .

[1]. Cai Xiong, et al. Deazapurines, thienopyrimidines and furopyrimidines as phosphoinositide 3-kinase inhibitors with a zinc binding moiety and their preparation and use in the treatment of diseases. From U.S. Pat. Appl. Publ. (2012), US 20120088764 A1 20120412.