Deriglidole是外周肾上腺素能受体拮抗剂，对α2肾上腺素受体具有高亲和力。
CAS：122830-14-2
分子式：C16H21N3
分子量：255.36
纯度：98%
存储：Store at -20°C

Background:

Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors.

Deriglidole is a selective α2-receptor inhibitor. Deriglidole inhibits [3H]Clonidine and [3H]Idazoxan but not [3H]Prazosin binding to rat cortical and human platelet α2-adrenoceptors and is more selective than Idazoxan for peripheral receptors[1].

[1]. Natali A, et al. Effects of acute alpha 2-blockade on insulin action and secretion in humans. Am J Physiol. 1998 Jan;274(1 Pt 1):E57-64.