Luteolin 7-O-glucuronide 可作为有效的自由基清除剂，能够抑制基质金属蛋白酶 (MMP) 的活性，其对 MMP-1，MMP-3，MMP-8，MMP-9，MMP-13的IC50 值分别为 17.63，7.99，11.42，12.85，0.03 μM。
CAS：29741-10-4
分子式：C21H18O12
分子量：462.36
纯度：98%
存储：Store at -20°C

Background:

Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively. MMP-1|17.63 μM (IC50)|MMP-3|7.99 μM (IC50)|MMP-8|11.42 μM (IC50)|MMP-9|12.85 μM (IC50)|MMP13|0.03 μM (IC50)

[1]. CrascÌ L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911.