Bigelovin is a naturally occuring sesquiterpene lactone isolated from Inula helianthus aquatica, and has been reported to induce apoptosis and show anti-inflammatory and anti-angiogenic activities. It can cause cell cycle arrest and subsequently induce apoptosis in cancer cells. It is formerly known as a potent cytotoxic sesquiterpene lactone from Inula sp. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.

纯度：≥98%

CAS：3668-14-2