BI-3812是一种高效的BCL6抑制剂，能够抑制BCL6的BTB结构域，IC50值≤3nM，具有抗肿瘤活性。
CAS：2166387-64-8
分子式：C26H32ClN7O5
分子量：558.03
纯度：98%
存储：Store at -20°C

Background:

BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity.

BI-3812 is a BCL6 inhibitor, with an IC50 of ≤3 nM. BI-3812 shows an IC50 of 40 nM for the cellular BCL6[1].

[1]. Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875.