mitochondrial respiratory complex II (succinate dehydrogenase) inhibitor
CAS:504-88-1
分子式:C3H5NO4
分子量:119.08
纯度:98%
存储:Store at -20°C
Background:
3-Nitropropanoic acid is an irreversible inhibitor of succinate dehydrogenase.
参考文献:
[1]. Huang LS, et al. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J Biol Chem. 2006 Mar 3;281(9):5965-72.