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Isoacteoside
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isoacteoside图片
CAS NO:61303-13-7
包装:20mg
规格:98%
市场价:2407元
分子量:624.59

产品介绍
Extracted from Cistanche deserticola Y.C. Ma;Suitability:Ethanol,methanol,ethyl acetate,DMSO;Store the product in sealed,cool and dry condition
CAS:61303-13-7
分子式:C29H36O15
分子量:624.59
纯度:98%
存储:Store at -20°C

Background:

Isoacteoside is a natural compound which exhibit significant inhibition of advanced glycation end product formation with IC50 values of 4.6-25.7 μM, compared with those of aminoguanidine (IC50=1,056 μM) and quercetin (IC50=28.4 μM) as positive controls.IC50 value:Target:In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 μM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 μM) and quercetin (IC50=7.2 μM).


参考文献:
[1]. Yu SY, et al. Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo. Planta Med. 2013 Dec;79(18):1705-9.