(+)-(3R,8S)-Falcarindiol是从胡萝卜中得到的聚乙炔，具有抗分歧杆菌(antimycobacterial)作用，对MycobacteriumtuberculosisH37Ra的最低抑制浓度MIC和IC50值分别为24μM和6μM。具有抗肿瘤和抗炎作用。
CAS：225110-25-8
分子式：C17H24O2
分子量：260.37
纯度：98%
存储：Store at -20°C

Background:

(+)-(3R,8S)-Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC50 of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra[1][2]. Antineoplastic and anti-inflammatory activity[2]. IC50: 6 μM (Mycobacterium tuberculosis H37Ra)[1]

[1]. O’Neill T, et al. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins. J Ethnopharmacol. 2013 May 2;147(1):232-7. [2]. Kobaek-Larsen M, et al. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer. BMC Res Notes. 2018 Jun 27;11(1):411.