BLU-782 (BLU782) is a novel potent, selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of<10 nm.
CAS:2141955-96-4
分子式:C31H42N6O4
分子量:562.715
纯度:98%
存储:Store at -20°C
Background:
BLU-782 (BLU782) is a novel potent, selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of <10 nM. BLU-782 is a development candidate for the treatment of fibrodysplasia ossificans progressiva, example 876 in patent WO 2017181117 A1
Reference:
1. PCT Int. Appl. (2017), WO 2017181117 A1 20171019. .