12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid.
CAS:108437-64-5
分子式:C20H30O3
分子量:318.5
纯度:98%
存储:Store at -20°C
Background:
12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via a leukotriene B4 receptor or a common activation sequence.