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Phosphatidylethanolamines(soy)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phosphatidylethanolamines(soy)图片
CAS NO:97281-51-1
规格:98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品介绍
Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids.
CAS:97281-51-1
分子量:
纯度:98%
存储:Store at -20°C

Background:

Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E. coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. Phosphatidylethanolamines (soy) is a mixture of phosphatidylethanolamines isolated from soy with various fatty acyl groups at the sn-1 and sn-2 positions.


参考文献:
[1]. Vance, J.E., and Tasseva, G. Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells Biochim. Biophys. Acta 1831(3), 543-554 (2013).
[2]. Bogdanov, M., Sun, J., Kaback, H.R., et al. A phospholipid acts as a chaperone in assembly of a membrane transport protein J. Biol. Chem. 271(20), 11615-11618 (1996).
[3]. Deleault, N.R., Piro, J.R., Walsh, D.J., et al. Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids Proc. Natl. Acad. Sci. U.S.A. 109(22), 8546-8551 (2012).