CAS NO: | 6754-13-8 |
包装: | 1mg |
规格: | 98% |
市场价: | 5647元 |
分子量: | 262.3 |
Background:
Helenalin is a sesquiterpene lactone first isolated from various species of Arnica. It has anti-inflammatory effects, most notably by inhibiting gene expression mediated by NF-κB at doses from 1 to 20 µM. Like other sesquiterpene lactones, helenalin can modify sulfhydryl groups of cysteine residues and it alkylates these groups on the p65 subunit of NF-κB. It also suppresses the proliferation of cancer cells through multiple mechanisms, including the prevention of signaling through NF-κB. Helenalin has antibacterial and anti-protozoal activities.