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Teleocidin A1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Teleocidin A1图片
CAS NO:70497-14-2
规格:98%
分子量:437.6
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Teleocidin A1, also known as lyngbyatoxin A, is a fungal metabolite that has been isolated from S.
CAS:70497-14-2
分子式:C27H39N3O2
分子量:437.6
纯度:98%
存储:Store at -20°C

Background:

Teleocidin A1, also known as lyngbyatoxin A, is a fungal metabolite that has been isolated from S. mediocidicus and is the R enantiomer of (S)-teleocidin A. It acts as a tumor promoter, inducing ornithine decarboxylase activity in mouse skin, increasing adhesion of HL-60 human leukemia cells (ED50 = 7 ng/ml), and inducing tumor formation in 87% of mice after 30 weeks when administered at a dose of 3 µg twice per week. Teleocidin A1 also increases the production of prostaglandins and the turnover of choline in HeLa cells when used at concentrations ranging from 6 to 20 ng/ml. It is a substrate for the methyltransferase TleD in Streptomyces where it is converted to teleocidin B.