Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone.
CAS：146062-45-5
分子式：C19H18N2O4S
分子量：370.4
纯度：98%
存储：Store at -20°C

Background:

Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone . Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.