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EOS(d18:1/32:1/18:2)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
EOS(d18:1/32:1/18:2)图片
CAS NO:1318771-31-1
规格:98%
分子量:1038.8
包装与价格:
包装价格(元)
100ug电议
250ug电议
500ug电议

产品介绍
EOS is a ceramide found in the outer layer of the epidermis in mammals.
CAS:1318771-31-1
分子式:C68H127NO5
分子量:1038.8
纯度:98%
存储:Store at -20°C

Background:

EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid . The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the ω-hydroxy end of the very long-chain fatty acid to covalently bind the protein layer, forming the corneocyte lipid envelope and sealing the gap between the extracellular lipid lamellae and the cornified cell envelope of the corneocyte.