7-hydroxy Warfarin is a metabolite of (-)-warfarin, which is a more potent vitamin K antagonist than (+)-warfarin.
CAS:17834-03-6
分子式:C19H16O5
分子量:324.3
纯度:98%
存储:Store at -20°C
Background:
7-hydroxy Warfarin is a metabolite of (-)-warfarin , which is a more potent vitamin K antagonist than (+)-warfarin . Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9). Stereoselective metabolism also occurs, and CYP2C9 is the primary enzyme responsible for metabolism of (-)-warfarin to 7-hydroxy warfarin.