Herbicidin A is an adenine nucleoside antibiotic originally isolated from S.
CAS:55353-31-6
分子式:C23H29N5O11
分子量:551.5
纯度:98%
存储:Store at -20°C
Background:
Herbicidin A is an adenine nucleoside antibiotic originally isolated from S. saganonensis that exhibits herbicidal activity, particularly against dicotyledonous plants. It prevents rice seed germination (MIC = 6.25 ug/ml) and completely protects young rice plants from X. oryzae-induced leaf blight when applied at 100 ppm. In HEK293 cells, herbicidin A inhibits TNF-α-induced NF-κB activity and induces cytotoxicity (IC50s = 1.8 and 2.7 uM, respectively).