AZD-5069是有效的CXCR2chemokine受体拮抗剂，用于癌症治疗。
CAS：878385-84-3
分子式：C18H22F2N4O5S2
分子量：476.52
纯度：98%
存储：Store at -20°C

Background:

AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.

AZD-5069 (Compound 2) acts as CXCR2 antagonist by inhibition of [125I]-IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye[1].

[1]. Norman P. Evidence on the identity of the CXCR2 antagonist AZD-5069. Expert Opin Ther Pat. 2013 Jan;23(1):113-7.