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Tedizolid Phosphate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tedizolid Phosphate图片
CAS NO:856867-55-5
规格:98%
分子量:450.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Tedizolid phosphate is a prodrug form of tedizolid, an antibiotic with activity against Gram-positive bacteria.
CAS:856867-55-5
分子式:C17H16FN6O6P
分子量:450.3
纯度:98%
存储:Store at -20°C

Background:

Tedizolid phosphate is a prodrug form of tedizolid, an antibiotic with activity against Gram-positive bacteria. Tedizolid phosphate is rapidly converted by non-specific phosphatases to tedizolid, which inhibits the growth of S. aureus, S. epidermidis, E. faecalis, E. faecium, S. pneumoniae, and S. pyogenes (MICs = 0.25-1 μg/ml). In vivo, tedizolid phosphate (15 mg/kg) reduces vegetation titer in a rabbit model of aortic valve endocarditis caused by methicillin-resistant S. aureus (MRSA). It also reduces densities of methicillin-susceptible S. aureus and MRSA infection in a mouse model of catheter-related biofilm infection and increases survival in a rabbit model of MRSA necrotizing pneumonia.