您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > PCTR1
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PCTR1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PCTR1图片
CAS NO:1810710-59-8
规格:98%
分子量:649.8
包装与价格:
包装价格(元)
10ug电议
25ug电议
50ug电议
100ug电议

产品介绍
Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid.
CAS:1810710-59-8
分子式:C32H47N3O9S
分子量:649.8
纯度:98%
存储:Store at -20°C

Background:

Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It also reduces the levels of PGE2 , PGD2 , and TXB2 in peritoneal exudates.