1-Deoxynojirimycin is a glucose analog that potently inhibits α-glucosidase I and II.
CAS:79206-51-2
分子式:C12H23NO6
分子量:277.3
纯度:98%
存储:Store at -20°C
Background:
1-Deoxynojirimycin is a glucose analog that potently inhibits α-glucosidase I and II. N-5-Carboxypentyl-1-deoxynojirimycin is a ligand used for the purification of glucosidase I and II. The carboxypentyl groups allows linkage of the inhibitor with resins for affinity chromatography. N-5-Carboxypentyl-1-deoxynojirimycin is at least as potent an inhibitor of glucosidase as 1-deoxynojirimycin (Kis = 0.45 and 2.1 µM, respectively, for pig liver glucosidase I).