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Falcarinol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Falcarinol图片
CAS NO:21852-80-2
规格:98%
分子量:244.4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Falcarinol is a C17-polyacetylene produced by the Apiaceae family that has antimicrobial properties due to its inhibition of fatty acid biosynthesis.
CAS:21852-80-2
分子式:C17H24O
分子量:244.4
纯度:98%
存储:Store at -20°C

Background:

Falcarinol is a C17-polyacetylene produced by the Apiaceae family that has antimicrobial properties due to its inhibition of fatty acid biosynthesis. Falcarinol binds to the human recombinant cannabinoid (CB) receptors, CB1 and CB2, (Kis = 594 and 2,100 nM, respectively) in an [3H]anandamide displacement assay in HEK293 cells. It differentially modulates synaptic and extrasynaptic GABAA receptors in a recombinant HEK293 system. In vitro assays of ATPase activity demonstrate that falcarinol inhibits breast cancer resistance protein ATP-binding cassette sub-family G member 2 (ABCG2; IC50 = 79.3 μM), a drug efflux transporter and mediator of drug resistance. Falcarinol (6.88 μg/g feed) also inhibits aberrant crypt foci by 26.6% in azoxymethane-induced rats.