Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib.
CAS:1347304-18-0
分子式:C22H18N4O2S
分子量:402.5
纯度:98%
存储:Store at -20°C
Background:
Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib . It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.