12-Deoxywithastramonolide is a withanolide found in W.
CAS:60124-17-6
分子式:C28H38O6
分子量:470.6
纯度:98%
存储:Store at -20°C
Background:
12-Deoxywithastramonolide is a withanolide found in W. somnifera roots. It has anti-inflammatory activity, reducing Tnf-α and increasing Il-10 production in mice following oral administration at doses ranging from 50-200 mg/kg. 12-Deoxywithastramonolide also reduces the growth of A549 lung and HT-29 colorectal cancer cells (IC50s = 47.1 and 29.8 μM, respectively).