Background:

Histamine (phosphate) diphosphate is a potent agonist of histamine receptors and vasodilator. It can activate nitric oxide synthetase.

参考文献:
[1]. Rietveld S et al.The influence of respiratory sounds on breathlessness in children with asthma: a symptom-perceptionapproach.
[2]. Rietveld S et al.The influence of respiratory sounds on breathlessness in children with asthma: a symptom-perceptionapproach. Health Psychol. 1997 Nov;16(6):547-53.