Amrinone is an inhibitor of phosphodiesterase 3 (PDE3; IC50 = 19.5 μM).
CAS:60719-84-8
分子式:C10H9N3O
分子量:187.2
纯度:98%
存储:Store at -20°C
Background:
Amrinone is an inhibitor of phosphodiesterase 3 (PDE3; IC50 = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. Amrinone (1-10 mg/kg) has positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.